Detoxination White Paper

Ever since the industrial revolution and the prevalence of petroleum-based chemicals (including pharmaceuticals), diseases have exponentially increased.  The correlation between diseases and the growing use of heavy metals and synthetic chemicals is alarming.  Recent studies have conclusively proven that our natural detoxification pathways have not adapted to these toxins, called xenobiotics (substances foreign to the body), adequately enough to be safely processed.  In other words, these lipophilic, or fat soluble, xenobiotics are not fully converted to water soluble waste to be eliminated via urine or feces.   Therefore, in order to protect the vital organs, the unhandled xenobiotics become sequestered in our adipose tissues (body fat) where they cause mitochondrial dysfunction in fat cells.

The result of this damage, as well as the deficiency in nutritional building blocks from poor diet, manifests in most inflammatory diseases, autoimmune disorders, endocrine disorders, degenerative neurological diseases, and many cancers.  Symptoms include chronic pain, chronic fatigue, brain fog, insomnia, obesity, anxiety, depression, migraines, and many more common conditions.

In 1982, Dr. David E. Root pioneered the use of a sauna-based therapy, first developed by L.R. Hubbard and had been widely used for drug addiction, to treat workplace chemical and radiation exposure injuries.   For over 35 years Dr. Root has effectively administered this protocol personally to around 4,000 patients, and supervised detox programs both here and abroad.

Advancements in technology and research have further improved the efficacy of this unique protocol, and it is now offered as a preventive care modality called Detoxination®.  The protocol consists primarily of niacin, exercise, and sauna in daily 2-hour sessions over a two week period.  Other supporting elements include polyunsaturated oils, lecithin, electrolytes, vitamins and minerals to replenish those lost to sweat, and binders consisting of activated charcoal, Bentonite clay, and/or micronized zeolite.

The goal of Detoxination is to first mobilize fat-stored xenobiotics into the bloodstream, increase blood circulation with exercise to deliver the mobilized toxins to the dermis layers, and then eliminate the majority of these toxins through sebaceous sweat from sauna.  While some toxins may permeate the lining of the GI tract, binders are provided in order to absorb or adsorb these before they undergo enterohepatic recirculation (reprocessing by the liver and kidneys).

Niacin, or Vitamin B3, is the key component required to mobilize toxins from fat cells.  Only pure, immediate release nicotinic acid can be used for Detoxination.  Titrated niacin doses set up conditions for a substantial increase in toxin mobilization from fat cells by inducing a state called rebound lipolysis.

Dr. Root and his colleagues have published many peer-reviewed papers, some of which have been cited in over 25 other papers and one medical text, presenting the results from several detox projects:

1985-1987 – Capacitor workers in Semič, Slovenia contaminated by PCBs

2003-2007 – New York Rescue Workers Detoxification Project which treated over 1,000 First Responders, volunteers, and residents from Ground Zero after 9/11.

2007-2010 – The Utah Meth Cops Project funded by the State of Utah under supervision of Attorney General Mark Shurtleff to treat 68 police officers exposed to solvents used in the manufacture of methamphetamine.


Other notable projects involving Dr. Root include:

1983-1985 – Dr. Root, a Vietnam veteran himself, personally treated several Vietnam veterans exposed to the defoliant Agent Orange.  Excepted from an article by Dr. Joseph Mercola from May, 2014, he states, “Dr. David Root has the most experience detoxifying the veterans with Agent Orange exposure in Vietnam. He used niacin (vitamin B3) as a way to mobilize fat and free up toxic chemicals locked in all lipophilic fatty tissues, i.e. the fat and in your brain.”

A former Marine who fought in Vietnam and was exposed to Agent Orange and other toxins said, “the program has changed my life, my physical well-being and my attitude toward a much better existence…. There is hope for those Vietnam vets who are still in the Vietnam War syndrome after being out of the war.”

Another Vietnam veteran wrote, “Memory is much improved, mind clear. I visualized that all of the Agent Orange, arsenic, filthy food and water I consumed in Vietnam came out of me here. Hallelujah! Headaches are gone — not one. I feel like I’d have to ram my head into a wall to get one ([they were] very frequent before). Back and neck pain are gone. Sleeping well. Cough gone. Overall sense of well-being is beyond description!”

2010-2015 – Gulf War Illness: Evaluation of an Innovative Detoxification Program, funded by government grant, studied 32 veterans with Gulf War Illness.  This project was funded after several presentations to the CDC and the Presidential Special Oversight Board for Department of Defense Investigations of Gulf War Chemical and Biological Incidents by Dr. Root in the late ‘90s. Currently awaiting study results, however, sources indicate favorable results throughout the participant group.


The Detoxination Protocol is now administered by Daniel Root, the son of Dr. David Root, at their center in Rancho Cordova, California.  Daniel Root is the co-host of a weekly radio talk show, The Get Detoxinated! Show on 105.5 FM at 10 p.m. on Wednesdays, and the author of Sauna Detoxification Using Niacin:  Following The Recommended Protocol Of Dr. David E. Root available at  A video tutorial course is now available at, as well (see sample video explaining rebound lipolysis) .